不可救药

He has an incurable and widespread nepotism.

他们有药，到处蔓延裙带主义。

They are trying to cure him of his drug addiction but he is beyond hope.

他们想治愈他毒瘾, 但是他已经药了。

My children are hopelessly addicted to television.

我几个孩子都成了电视迷,简直是药了。