肿瘤基因

The trisomic, colon cancer mice had 44% fewer intestinal tumors than the colon cancer mice that did not have the extra 108 genes.

结果携带结肠癌基因的小鼠发生肠道肿瘤的机率比那些没有携带额外的108个基因而仅携带有结肠癌基因的小鼠少44%。

Despite a high morphological similarity, tumors with allelic loss on the short arm of chromosome 1 (1pLOH) are more chemosensitive than those without 1pLOH.

尽管两种肿瘤在形态学极其相似，但是1号染色短臂等位基因丢失的肿瘤比没有丢失的药物敏感性要高得多。

Neutrophil gelatinase-associated lipocalin(NGAL) is a novel member of the lipocalin family and may be a new human oncogene, but the regulation mechanism of NGAL was not clear in the cancer.

NGAL(neutrophil gelatinase-associated lipocalin)是lipocalin家族的一个新成员，可能是人类的一种新癌基因，但其在肿瘤中的表达调控机制尚不清。

The idea that a lack of methyl on the DNA can lead to human cancer is still just a hypothesis, and in any case oncologists have no drugs that can correct genome-wide undermethylation.

DNA少甲基会导致人类出现癌症的想法，还只是个假说，肿瘤学家手头也没有任何药物，可以用来改善基因组的全面去甲基化。