In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

性黑患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，切除术对有肺性黑色患者仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别子算术的控制后，转移瘤切除术对有肺转移性黑色瘤患者仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转移切除术对有肺转移性黑色仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的，转移瘤切除术对有肺转移性黑色瘤患者仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，症相关的环境缺乏合适的调机来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移黑瘤患者可发生全身黑变（散黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转移瘤切除术对有肺转移黑色瘤患者仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性瘤患者可发生全身性皮肤（皮肤播散性），常存在尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转移瘤切除术对有肺转移性色瘤患者仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算的控制后，转移瘤切除有肺转移性黑色瘤患者仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转移瘤切除术对有肺转移性黑色瘤患者仍有显著的生优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

黑瘤发生全身皮肤黑变（皮肤播散黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，瘤切除术对有肺黑色瘤仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。