In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性瘤患者可发生全身性皮肤变（皮肤播散性变），通常存在。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

其他鉴别风险因子算术控制后，转移瘤切除术对有肺转移性色瘤患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关环境缺乏合适调控机制来维持一个正常细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他险因子算术控制后，移瘤切除术对有肺移性黑色瘤患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关环境缺乏合适调控机制来维持一个正常细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转可发生全身皮肤变（皮肤播散变），通常存在尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转切除术对有肺转色仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

黑瘤发生全身皮肤黑变（皮肤播散黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，瘤切除术对有肺黑色瘤仍有显著的生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转移瘤切除术对有肺转移性黑色瘤患者仍有显著的存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关的环境缺乏合适的调控机制来维持一个正常的细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他险因子算术控制后，移瘤切除术对有肺移性黑色瘤患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关环境缺乏合适调控机制来维持一个正常细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他鉴别风险因子算术控制后，转移瘤切除术对有肺转移性黑色瘤患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症环境缺乏合适调控机制来维持一个正常细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他鉴别风险因子算术控制后，转移瘤切除术对有肺转移性黑色瘤患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症环境缺乏合适调控机制来维持一个正常细胞表型。

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他鉴别风险因子算制后，转移切除对有肺转移性黑色患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关环境缺乏合适调机制来维持一个正常细胞表型。