Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

具有环丙基结构的三唑醇类化合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、三唑类、烯丙胺类、抗生素类等全身用抗真菌药的发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属三唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力库、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-三唑为原料，在稀碱存在下与二卤代烷反应合成10个新的标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

1，2，4三唑酮3（TO）衍生物的合成，结果表明TO在多种硝化条件下均可制得3硝基1，2，4三唑酮5（NTO），同时还合成TO的二取代硝基苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙的三唑醇类化合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、三唑类、烯丙胺类、抗生素类等全身用抗真菌药的研发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属三唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力库、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳-5-巯-1，3，4-三唑为原料，存下与二卤代烷反应合成了10个新的标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1，2，4三唑酮3（TO）衍生物的合成，果表明TO多种硝化条件下均可制得3硝1，2，4三唑酮5（NTO），同时还合成了TO的二取代硝苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

具有环丙基结构的三唑醇类化合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、三唑类、烯丙胺类、抗生素类等全身用抗真菌药的发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属三唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-三唑为原料，在稀碱存在下与烷反应合成了10个新的标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

了1，2，4三唑酮3（TO）衍生物的合成，结果表明TO在多种硝化条件下均可制得3硝基1，2，4三唑酮5（NTO），同时还合成了TO的取硝基苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙的三唑醇类化合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、三唑类、烯丙胺类、抗生素类等全身用抗真菌药的研发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属三唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力库、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳-5-巯-1，3，4-三唑为原料，存下与二卤代烷反应合成了10个新的标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1，2，4三唑酮3（TO）衍生物的合成，果表明TO多种硝化条件下均可制得3硝1，2，4三唑酮5（NTO），同时还合成了TO的二取代硝苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙基结构的唑醇类合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、唑类、烯丙胺类、抗生素类等全身用抗真菌药的研发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力库、菌立克种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-唑为原料，在稀碱存在下与二卤代烷反应合成10的标题合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究1，2，4唑酮3（TO）衍生物的合成，结果表明TO在多种硝条件下均可制得3硝基1，2，4唑酮5（NTO），同时还合成TO的二取代硝基衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙基结构醇类化合物抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪类、类、烯丙胺类、抗生素类等全身用抗真菌药研发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

醇属类杀菌剂,可抑制真菌中麦角甾醇生物合成,主要商品有:立克莠、富力库、菌立克种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-，在稀碱存在下与二卤代烷反应合成了10个新标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1，2，4酮3（TO）衍生物合成，结果表明TO在多种硝化条件下均可制得3硝基1，2，4酮5（NTO），同时还合成了TO二取代硝基苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

具有环丙基结构的三唑醇类化合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、三唑类、烯丙胺类、抗生素类等全身用抗真菌药的发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属三唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-三唑为原料，在稀碱存在下与烷反应合成了10个新的标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

了1，2，4三唑酮3（TO）衍生物的合成，结果表明TO在多种硝化条件下均可制得3硝基1，2，4三唑酮5（NTO），同时还合成了TO的取硝基苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙基结构的唑醇类合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑类、唑类、烯丙胺类、抗生素类等全身用抗真菌药的研发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属唑类杀菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力库、菌立克种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-唑为原料，在稀碱存在下与二卤代烷反应合成了10个新的合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1，2，4唑酮3（TO）衍生物的合成，结果表明TO在多种硝条件下均可制得3硝基1，2，4唑酮5（NTO），同时还合成了TO的二取代硝基苯衍生物。

Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙基结构三唑醇化合抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪唑、三唑、烯丙胺、抗全身用抗真菌药研发进展及市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

唑醇属三唑杀菌剂,可抑制真菌中麦角甾醇合成,主要商品有:立克莠、富力库、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-三唑为原料，在稀碱存在下与二卤代烷反应合成了10个新标题化合。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1，2，4三唑酮3（TO）衍合成，结果表明TO在多种硝化条件下均可制得3硝基1，2，4三唑酮5（NTO），同时还合成了TO二取代硝基苯衍。