Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基甲酸酯化和环合等反应合成目标化合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白乙酰化和去乙酰化由一对互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基甲酸酯化和环合等反应合成目标化合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组酰化和去酰化由一对功能相互拮抗的酶——组酰基转移酶和组去酰化酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水、乙酰化、环化、氧化、脱化、酰化、环氨基甲化和环合等反应合成目标化合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、乙酰、环碳、氧、脱碳、酰、环氨基甲环合等反应合成目标合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白乙酰去乙酰由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶组蛋白去乙酰酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、、环碳酸酯、氧、脱碳酸酯、、环氨基甲酸酯和环等反应成目标物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白和去由一对功能相互拮抗的蛋白酶——组蛋白基转移酶和组蛋白去酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、、环碳酸酯、氧、脱碳酸酯、、环氨基甲酸酯和环合等反应合成目标合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白和去一对功能相互拮抗的蛋白酶——组蛋白基转移酶和组蛋白去酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、乙酰化、碳酸酯化、氧化、脱碳酸酯化、酰化、甲酸酯化和合等反应合成目标化合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组乙酰化和去乙酰化由一对功能相互拮抗的酶——组乙酰转移酶和组去乙酰化酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基甲酸酯化和环合等反应合成目标化合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白乙酰化和去乙酰化由能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。

Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以拉霉素为起始原料,经水解、、环碳酸酯、氧、脱碳酸酯、、环氨基甲酸酯和环合等反应合成目标合物。

The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋白和由一对功能相互拮抗的蛋白酶——组蛋白基转移酶和组蛋白酶负责。