Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊时给予别嘌呤醇静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是由于型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中种含氮碱基，具有嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

种以黄素核苷（黄素腺嘌呤二核苷FAD或黄素单核苷FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这类化合物之所以具有很好杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘(NADH)制用而阻断了线粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶制剂、促进尿排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮基，有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，有烷剂和嘌呤类似的双相功能可在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类合物之所有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的种含氮碱基，具有个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS的关。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

类化合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，有烷剂和嘌呤类似的双相功能可在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类合物之所有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧酶抑制剂、促进酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中含氮碱基，具有个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这类化合物之所以具有很好杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)抑制用而阻粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核（黄素腺嘌呤二核FAD黄素单核FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘(NADH)抑制用而阻断了线粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿排泄药脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一个结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别醇及静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素苷酸（黄素腺苷酸FAD或黄素单苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的氮碱基，具有个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这类化合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物，他选择包括他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。