She knows physiology from beginning to end.

对生理学这门学科了如。

She knows the layout of the back streets like the back of her hand.

对那些偏僻的街道了如。

Tony is very hot on local history.

尼对当地历史了如。

She knows every nook and cranny of the city, so she’s the perfect guide.

对这个城市了如，让道是再好不过了。