Objective To study the analgesic effect and the physical dependence of verticinone, which is an isosteroidal alkaloids isolated from Fritillariae Bulbus.
The afferent nerve fibers were excited possibly belong to the different functional groups.Excitation of each group of fibers will cause algesia or analgesia respectively.
The function of analgesia of the Oral Rehydration of Ophidic Distille is tested by the method of twisting the mouse, radiating the mouse, trigeminus electronic of rats.
Conclusions: IPO has no irritability and allergia, least or no toxicity, but better functions of anti-inflammation, abirritation and detumescence as well as high safety in administration.