But President Theodore Roosevelt, who used saccharin after his doctor prescribed him a sugar-free diet, personally intervened to prevent it being banned.
Not all sugar-free carbonated drinks contain alternative sweeteners, so check the ingredient list for aspartame, saccharin, sucaralose and acesulfame potassium.
Elinav's findings on sucralose and saccharin go against decades of public health orthodoxy, which says artificial sweeteners have no effect on blood sugar.
In 1908, Harvey Wiley, who was then the head of the US Food and Drug Administration, sought to have saccharin eliminated from the food supply as an impure additive.
She also says that " There is no evidence to suggest that low-calorie sweeteners, such as saccharin, aspartame and sucralose, are harmful or bad for you" .