Objective To explore the operative result of intrarectal proctoptosis accompanying hernia of pelvic floor due to common outlet obstructive constipation(OOC).
This is particularly dangerous because the displaced cerebellum can push onto the brainstem affect neurons responsible for breathing and cardiac function.
Supratentorial herniation refers to displacement of the cerebrum which is above the tentorium, and infratentorial herniation refers to herniation of the cerebellum which is below the tentorium.
So, brain herniation can be caused by either a focal mass effect, like the arterial bleed, or a diffuse mass effect, depending on whether the problem is in one area or involves the entire brain.
The team at UCL also grew organoids from fetuses with congenital diaphragmatic hernia, a birth defect that compresses the lungs and prevents them from properly developing as a child grows in the womb.
In upward herniation, there's a displacement of the cerebellum upward, through a notch in the tentorium cerebelli, while in tonsillar herniation, parts of the cerebellum slip down through an opening in the skull called the foramen magnum.