Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明线醛
酶是
内催
硝酸甘油生物转
的主要途径,线
醛
酶同时具有
酶和酯酶的催
活性,其酯酶活性可以通过将硝酸甘油
硝形成一氧
氮,进而血管扩张。