Zymogen granules might fuse with lysosomes bringing trypsinogen into contact with lysosomal digestive enzymes.

酶原颗粒可能会和溶酶体融合，使胰蛋白酶原与溶酶体消化酶接触。

First, the cytoplasmic granules fuse with the phagosome to form the phagolysosome.

首先，胞质颗粒与吞噬体融合形成吞噬溶酶体。

Those vesicles then get transported to an organelle within the cell called the lysosome.

之后囊泡被运输到细胞内被称为溶酶体的细胞器中。

Phagocytosis of apoptotic cells or bodies by adjacent healthy cells, either parenchymal cells or macrophages.

亡小体在溶酶体内速降解，相邻细胞通或增殖以取代现已清除的亡细胞占据的原有空隙。

It has the ability to stop phagolysosomal fusion, and survive and replicate inside alveolar macrophages.

它可以阻止吞噬体和溶酶体融合，从而在肺泡巨噬细胞内生存并增殖。

Where the sacks get degraded and the contents are made available for reuse.

在溶酶体里，这些囊泡会被降解，里面的物质也就可以被重新利用。

GM2 is found mainly in neurons, so without HEX-A, it accumulates inside lysosomes.

GM2通常分布在神经元中，因此如果HEX-A缺失，GM2就会在溶酶体中积蓄。

The leftover bubble will be broken down, by the cell's lysosomes, and its pieces recycled over and over again.

剩余的泡沫将会被分解，溶酶体负责这项工作，气泡的残骸会回收、重复使用。

However, Legionella has a type IVB secretion system, which uses effector proteins to prevent phagolysosomal fusion.

但是，军团菌有一套IVB分泌系统，会利用效应蛋白阻碍吞噬体和溶酶体的融合。

The granules contain molecules that lower the pH of the phagolysosome, making it very acidic, and that kills about 2% of the pathogens.

这些颗粒含有降低吞噬溶酶体pH值的分子，使其呈强酸性，以杀死大约2%的病原体。

With most cases, the macrophage then fuses the phagosome with a lysosome which has hydrolytic enzymes that can pretty much break down any biochemical molecules.

大部分情况下，巨噬细胞会将吞噬小体和溶酶体融合到一起；溶酶体中含有水解酶可以很大程度上分解生物化学分子。

All right, as a quick recap, Tay-Sachs disease is a lysosomal storage disease that results in a buildup of GM2 ganglioside in neurons of the central nervous system.

好，快速回顾下：Tay-Sachs病是一种溶酶体贮积病，能引起中枢神经系统神经元中GM2神经节苷脂贮积。

Once it reaches the lungs, it gets ingested by alveolar macrophages and inside macrophages, it gets wrapped up in a vesicle called phagosome, which normally merges with lysosomes to kill invading bacteria.

进入肺内后，它就会被肺泡巨噬细胞吞噬；在巨噬细胞内，它被包裹在称为吞噬体的囊泡中，通常吞噬体会与溶酶体融合，清除入侵的细菌。