And the compound that's left over from this process, an acid called isovaleric acid, starts to build up.

未分解的分叫做异戊酸，开始积累下来。

Here, patients have a genetic mutation that leads to a deficiency in an enzyme called isovaleric co-enzyme A dehydrogenase.

由于患者基因突变会导致缺乏一酶，被称为——异戊酸辅酶A脱氢酶。

Isovaleric acid smells kind of like cheese, and it's the same chemical that makes your sweaty feet smell.

异戊酸闻起来像奶酪，让你有臭脚味的化学物质。

But while isovaleric acid isn't exactly pleasant to smell outside your body, it can be downright damaging to the inside.

然而这异戊酸让人很不愉快，能够彻底的损害身。

Some were exposed to valproic acid, a drug used to treat bipolar disorder and migraines that is known to induce autism in fetuses.

一些被暴露于丙戊酸中，这药物被用于治疗躁郁症和偏头痛，已知这疾病会诱发胎儿的孤独症。

It's not exactly clear why, but a build-up of isovaleric acid tends to have the most dramatic effects on the central nervous system.

现在还不清楚原因，但异戊酸的积累往往会对中枢神经系统产生剧烈的影响。

STEP 1 Consider switching from migraine medicine with valproic acid, which can make you eat more, to other migraine medicines that are less likely to increase your appetite, such as sumatriptan.

考虑代替含有丙戊酸成分的偏头痛药物，这药物会让你吃得更多，改为不会增加食欲的偏头痛药物，例如舒马曲坦。

There is, so far, no cure for isovaleric acidemia, but some treatments — like avoiding foods rich in leucine, and taking supplements of other, non-threatening amino acids — can help keep patients safe.

目前没有治疗异戊酸血症的方法，但一些疗法——比如避免进食白氨酸过多的食物，从其他物质中，比如没有威胁的氨基酸，能够保证患者安全。