Thus, the rationality standard of the research method in system science should be understood, that is, inter-level of structure, plantable and comprehensive.
This paper is a state-of-the-art overview of this technique and describes in three levels: molecular simulation; unit operation simulation and flowsheeting simulation.
They approach the subject matter from gene level to discuss the glycosyltransferase expression, and from the glycan and protein level to discuss the glycoform difference.