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Objective To investigate the synergistic analgesic action of rotundine combined with subthreshold dose of dolantin.

摘要目的观察罗通定与剂量哌替啶合用后对哌替啶镇痛作用的影

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Conclusion The combined administration of dolantin and rotundine has significant synergistic action of analgesia, with reduced dose of dolantin and decreased incidence of addiction.

罗通定与剂量派替啶合用可以强镇痛效果,从而减少派替啶的用量,药物依赖的发生概率。

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Methods The aqueous extract of all grass of Patrina villosa Juss was injected peritoneally to mice or that accompanied with suprathreshold or subthreshold dose of pentobarbital solution.

方法取白花败酱草水提取液分别单独、配伍使用阈上或剂量的戊巴比妥钠注入小鼠体内,观察小鼠的自发活动和睡眠时间,并将果与对照组进行比较、分析。

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