Cyanopyridine,intermediate of rimifon, was synthesized from 4-picoline using vanadium oxide as a catalyst in a fixed-bed reactor, reached 99% conversion of 4-picoline, 88% selectivity and 87.

以4甲基吡料,在固定床反应器中通过含氧化钒的化剂发生气固相接触氨氧化反应制备中间体4氰基吡,4甲基吡的转化率99%,4氰基吡的选择性88%,收率87。