melanoma

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑患者可发全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他鉴别风险因子算术控制后，转移切除术对有肺转移性黑色患者仍有显存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关环境缺乏合适调控机制来维持一个正常细胞表型。