Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究粒体乙醛脱氢酶是体催化硝酸甘油生物转化主要途径，粒体乙醛脱氢酶同时具有脱氢酶和酯酶催化活性，其酯酶活性可以通过将硝酸甘油脱硝形成一氧化氮，进而血管扩张。