It is associated with high perinatal mortality, thick fissured skin, marked ectropion (eyelid eersion), eclabium (eersion of the lips), and flexion deformities.

常有围期高死亡率、皮肤肥厚、显著的眼睑外翻、唇外翻和关节弯曲畸形。

Cases of porencephaly and global atrophyof the temporal lobe were highly related to prenatal or perinatal insults including preterm delivery and asphyxia.

而在及颞叶萎缩的病童似乎与前或周期的因素，如及窒息有关性。

Conclusions: In order to reduce the incidence of neonatal unconjugated hyperbilirubinemia, more emphasis should be put on the health care of the perinatal period.

做好围生期保健对预防新生儿高胆，降低其发病率有重要意义。