Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重要生物活性,根据作用机制,分为钙增敏剂、磷二酯酶抑制剂、环氧合酶抑制剂等,并用于相关疾病疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原酶抑制剂依帕司他合成工艺作了改进，使中间体绕丹宁乙率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是磷戊糖途径关键酶，催化二碳单元在酮糖（供体）和醛糖（受体）间转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重要的生物活性,根据作用机制的不同,可分为钙增敏剂、酯酶抑制剂、环氧合酶抑制剂等,并可用于相关疾病的疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原酶抑制剂依帕司他的合成工艺作了改，间体绕丹宁乙的收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是戊糖途径的关键酶，催化碳单元在酮糖（供体）和醛糖（受体）间的转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重要生物活性,根据作用机制不同,可分为钙增敏剂、磷酸二酯酶抑制剂、环氧合酶抑制剂等,并可用于相关疾病疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对搪还原酶抑制剂依帕司他合成工艺作了改进，使中间体绕丹宁乙酸收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是磷酸戊途径关键酶，催化二碳单元在酮（供体）（受体）间转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合有多种重要生活性,根据作用机制不同,可分为钙增敏剂、磷酸二酯酶抑制剂、环氧合酶抑制剂等,并可用于相疾病疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原酶抑制剂依帕司他合成工艺作了改进，使中间体绕丹宁乙酸收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是磷酸戊糖途键酶，催化二碳单元在酮糖（供体）和醛糖（受体）间转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化物具有多种重要生物活性,根据作用机制不同,可分为钙增敏剂、磷酸二酯制剂、环氧制剂等,并可用于相关疾病疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原制剂依帕成工艺作了改进，使中间体绕丹宁乙酸收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇是磷酸戊糖途径关键，催化二碳单元在酮糖（供体）和醛糖（受体）间转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重物活性,根据作用机制不同,可分为钙增敏剂、二酯酶抑制剂、环氧合酶抑制剂等,并可用于相关疾病疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原酶抑制剂依帕司他合成工艺作了改进，使中间体绕丹宁乙收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘转酮醇酶戊糖途径关键酶，催化二碳单元在酮糖（供体）和醛糖（受体）间转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重要的生物活性,根据作用机制的不同,可分为钙增敏剂、磷酸二酯酶抑制剂、环氧合酶抑制剂等,并可用于病的疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对原酶抑制剂依帕司他的合成工艺作了改进，使中间体绕丹宁乙酸的收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是磷酸戊糖途径的键酶，催化二碳单元在酮糖（供体）和糖（受体）间的转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重要的生物活性,根据作用机制的不同,可分为钙、磷酸二酯酶抑制、环氧合酶抑制等,并可用于相关疾病的疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原酶抑制依帕司他的合成工艺作了改进，使中丹宁乙酸的收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是磷酸戊糖途径的关键酶，催化二碳单元在酮糖（供）和醛糖（受）的转移。

Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

哒嗪酮类化合物具有多种重要的生物活性,根据作用机制的不同,可分为钙增敏剂、磷酸二酯酶抑制剂、环氧合酶抑制剂等,并可用于相的疗。

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

还原酶抑制剂依帕司他的合成工艺作了改进，使中间体绕丹宁乙酸的收率提高到76．4％。

Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

摘要转酮醇酶是磷酸戊糖途径的键酶，催化二碳单元在酮糖（供体）和糖（受体）间的转移。