Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，择包括黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中含氮碱基，具有个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这类化合物之所以具有很好杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)抑制用而阻粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷（黄素腺嘌呤二核苷FAD或黄素单核苷FMN）基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧酶抑制、促进尿排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊时给予别嘌呤醇静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是由于型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核（黄素腺嘌呤二核FAD黄素单核FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘(NADH)抑制用而阻断了线粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿排泄药脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中的一种含氮碱基，具有一环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别醇及静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素苷（黄素腺二苷FAD或黄素单苷FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是由于对还原型烟酰胺腺二(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄氧化酶抑制剂、促进尿排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以核苷酸（腺嘌呤二核苷酸FAD单核苷酸FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一化合物之所以具有很好杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)抑制用而阻断了线粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他嘌呤氧化酶抑制剂、促进尿酸排泄药脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在于DNA与RNA中一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并时给予别嘌呤醇碱化利尿是治疗TLS关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有杀虫活性，是由于对还原型烟酰胺腺嘌呤二核甘酸(NADH)抑制用而阻断了线粒体呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

Guanine A nitrogenous base found in DNA and RNA.Guanine has a pruine ring structure.

是存在DNA与RNA中的一种含氮碱基，具有一个嘌呤环结构。

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并予别嘌呤醇静脉碱化利尿是治疗TLS的关键。

Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients.

苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥用。

Flavoprotein A conjugated protein in which a FLAVIN (FAD or FMN) is the prosthetic group joined to a protein component.

一种以黄素核苷酸（黄素腺嘌呤二核苷酸FAD或黄素单核苷酸FMN）为辅基的结合蛋白。

Their biological activity is generally attributable to inhibition of NADH: ubiquinone oxidoreductase activity and thereby mitochondrial respiration.

这一类化合物之所以具有很好的杀虫活性，是还原型烟酰胺腺嘌呤二核甘酸(NADH)的抑制用而阻断了线粒体的呼吸。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适轻度皮疹者）。