HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯头原碱的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论草花煎煮过程中，双酯型和三酯型头生物碱除发生水解反应外，还发生酯交换反应生成双酯型和三酯型脂类生物碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂成本低、毒性,适用于头碱、中头碱、次头碱的提取分离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀聚合法合成了反头分子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形头。又称头或狼毒头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要头三羧循环中催化柠檬生成异柠檬。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧头碱的毒性较高，当它被肠内细菌转化为单酯型和脂类生物碱时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,乌头原碱的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论草乌花煎煮过程中，双酯型和酯型乌头生物碱除发生水解反应外，还发生酯交换反应生成双酯型和酯型脂类生物碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂成本低、毒性,适用于乌头碱、中乌头碱、次乌头碱的提取分离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀聚合法合成了反乌头酸分子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头或狼毒乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸羧酸循环中催化柠檬酸生成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧乌头碱的毒性较高，当它被肠内细菌转化为单酯型和脂类生物碱时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌头原的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程中，双酯型和三酯型乌头生物生水解反应外，还生酯交换反应生双酯型和三酯型脂类生物。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂本低、毒性,适用于乌头、中乌头、次乌头的提取分离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀聚法了反乌头酸分子印迹聚物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头或狼毒乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸酶在三羧酸循环中催化柠檬酸生异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧乌头的毒性较高，当它被肠内细菌转化为单酯型和脂类生物时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌头原碱的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程中，双酯型和三酯型乌头物碱除发水解外，还发酯交换成双酯型和三酯型脂类物碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂成本低、毒性,适用于乌头碱、中乌头碱、次乌头碱的提取分离及对照品的。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

乙腈为分散剂,采用沉淀聚合法合成了乌头酸分子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头或狼毒乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸酶在三羧酸循环中催化柠檬酸成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧乌头碱的毒性较高，当它被肠内细菌转化为单酯型和脂类物碱时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌头原碱转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程中，双酯型和三酯型乌头物碱除发水解反应外，还发酯交换反应成双酯型和三酯型物碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂成本低、毒性,适用于乌头碱、中乌头碱、次乌头碱分离以及对照品制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀聚合法合成了反乌头酸分子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头或狼毒乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸酶在三羧酸循环中催化柠檬酸成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型去氧乌头碱毒性较高，当它被肠内细菌转化为单酯型和物碱时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌头原碱的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程，型和三型乌头生碱除发生水解反应外，还发生交换反应生成型和三型脂类生碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法所用试剂成本低、毒性,适用于乌头碱、乌头碱、次乌头碱的提取分离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀法成了反乌头酸分子印迹微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头或狼毒乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸酶在三羧酸循环催化柠檬酸生成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

型的去氧乌头碱的毒性较高，当它被肠内细菌转化为单型和脂类生碱时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌原的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程，双酯型和三酯型乌生物除发生水解反应外，还发生酯交换反应生成双酯型和三酯型脂类生物。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法所用试剂成本低、毒性,适用于乌、乌、乌的提取分离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀聚合法合成了反乌酸分子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌。又称乌或狼毒乌。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌酸酶在三羧酸循环催化柠檬酸生成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧乌的毒性较高，当它被肠内细菌转化为单酯型和脂类生物时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌头原碱的转化率最高。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程中，双型和三型乌头物碱除发水解反应外，还发换反应成双型和三型脂类物碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂成本低、毒性,适用于乌头碱、中乌头碱、次乌头碱的提取离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙散剂,采用沉淀聚合法合成了反乌头酸子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头或狼毒乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸酶在三羧酸循环中催化柠檬酸成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双型的去氧乌头碱的毒性较高，当它被肠内细菌转化单型和脂类物碱时会使其毒性降低。

HPLC-MS analysis shows that the major hydrolysis products are benzoylaconine and aconine.

水解20h,苯甲酰乌头原碱的转化。

Conclusion Besides hydrolysis reactions, ester-exchange reactions happen for diester-aconitines and triester-aconitines in the decocting of FAK.

结论在草乌花煎煮过程中，双酯型和三酯型乌头生物碱除发生水解反应外，还发生酯交换反应生成双酯型和三酯型脂类生物碱。

This method was at low cost, harmless and suitable for extracting,separating and preparing mesaconitine,aconitine and hypaconitine.

方法中所用试剂成本低、性,适用于乌头碱、中乌头碱、次乌头碱的提取分离以及对照品的制备。

Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.

以乙腈为分散剂,采用沉淀聚合法合成了反乌头酸分子印迹聚合物微球。

Monkshood：Plant used in potions. Also known as aconite or wolfsbane.

舟形乌头。又称乌头乌头。

Aconitase is an enzyme that catalyzes the conversion of citric acid to isocitric acid in tricarboxylic acid cycle.

摘要乌头酸酶在三羧酸循环中催化柠檬酸生成异柠檬酸。

Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.

采用氯化钙、乌头碱致大鼠,哇巴因致豚鼠及肾上腺素致大白兔心律失常模型。

Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧乌头碱的性较，当它被肠内细菌转化为单酯型和脂类生物碱时会使其性降低。